Prescription drug abuse
PHYSIOTHERAPY AND PAIN-RELIEVING DRUG ABUSE
Prescription drug abuse (PDA) occurs when an individual (health professionals inclusive) uses a prescribed drug for non-medical purposes, use more than the prescribed dose or continue using it even after the amount prescribed by the physician was taken. Self-medication, on the other hand is the selection and use of drugs to relieve symptoms of a condition without a prescription.
Pain-relieving drugs misuse could be defined as the use of medications for non-medical reasons. Serious adverse health effects result from the abuse of prescription drugs or self-medication. Narcotics are natural opioids (pain-relieving) drugs that helps to reduce pain and anxiety, promotes drowsiness, induce anaesthesia prior to a surgery. These drugs are commonly prescribed to help individuals with chronic pain lead productive lives.
In Nigeria, results of several studies have shown that opioids are the commonly abused prescribed or self-medicated drugs for body pain. Reasons for this include financial constraint, lack of time, convenience, non-availability of doctors, free access to pharmaceutical shops, lack of knowledge of diagnosis and perception of symptoms to be minor enough to be amenable to self-medication or prescribed drugs. Prescribed opioids not properly monitored in terms of dosage, duration, frequency and side-effects could lead to high risk of overdose, dependency or addiction and fear of increased pain which invariably leads to abuse or withdrawal symptoms later in life especially if the drug is unavailable or no longer taken. Such withdrawal symptoms are diarrhoea, vomiting, involuntary leg movements, bone or muscular pain, cold flashes with goose bumps, lack of sleep (insomnia).
Causes of pain-relieving prescription drug abuse include the following: acute or chronic pain reduction; inaccessibility or unavailability of non-drug pain management service (physiotherapy, acupuncture, chiropractic), pleasure; legally available, obtainable and accessible pain-relieving drugs at markets, chemists, kiosks etc.; unpleasant withdrawal to developed dependency; increased pain intensity due to physical neglect; already built-up tolerance to present prescription; desire for relaxation; need for pleasure; desire for relieve of emotional pain.
Risk factors to pain-relieving prescription drug abuse include: biological factors (genetics, gender, ethnicity, inherent mental disorders) and environmental factors (socioeconomic status, family, quality of life, peer pressure, friends, history of physical, emotional and/or sexual abuse, anxiety, depression, stress).
Opioids taken exactly as prescribed is safe and rarely causes addiction. However prolonged use of opioids could lead to physical dependence as well as abuse of such drugs which invariably will require medical supervision. Examples of opioids commonly abused in Nigeria’s healthcare system include paracetamol, tramadol, diclofenac, pentasozine, dihydrocodeine (DF118), ibuprofen, demoline to mention a few. Others include gabapentin and pregabalin which are used to treat epilepsy and anxiety as well as reduce neuropathic pain. Combined with depressants, drugs for neuropathic pain cause sedation, drowsiness, respiratory failure and death. It is indeed noteworthy that most of these drugs are Over-The-Counter (OTC) drugs which makes them readily available to individuals.
Some of the subjective side-effects of PDA or DM are decreased pain sensation (that is, masking pain sensation without dealing with the cause of pain), constipation, drowsiness to mention a few. Objectively, the side-effects include drowsiness/sedation, nausea/vomiting, reduced respiratory rate, reduced blood pressure, depressed breathing/respiration, excessive mood swings, mental disorders (anxiety disorder, depression), euphoric feelings, feeling of overly and unusually energetic, tolerance, physical dependence/addiction, feeling of usual weakness leading to interference of Activities of Daily Living (ADL), behavioural and physiological changes, adverse reactions such as delayed wound healing, delayed repair of soft tissue injuries, soft tissue infections (cellulitis, abscess), low grade fever, delayed gastric emptying, muscle rigidity, increased pain sensitivity, myoclonus, immunologic and hormonal dysfunction. The risk of hip fracture has been associated with the use of strong opioids like fentanyl and moderately strong opioids like buprenorphine.
In addition, when opioids are taken with alcohol or other drugs, the effects could be fatal, they include; increase in body temperature, reduced respiratory rate, heart rate. In view of these, opioids when prescribed should be appropriately monitored due to the high risk of overdose and dependency which invariably leads to abuse.
Physiotherapists play a significant role in recognizing the signs and symptoms of prescription drug abuse. More so, they could screen patients when a problem is suspected and ensure that information on all drugs (prescribed or self-medicated) currently taken by patients are gotten. Thereafter, all findings should be reported to the referring medical doctor or primary care physician if the potential for drug abuse is suspected. The dangers of taking prescribed medication outside of the recommendation should be discussed with the patients.
Musculoskeletal pain (neck, shoulder, elbow, wrist, back, hip, knee, ankle pain) is among the common reasons for opioids usage. Its chronicity often leads to dependency and abuse. National health-care coverage of musculoskeletal pain is usually limited to low-value health care approaches such as prescription medications (mostly involving long-term use of pain-relieving drugs), simple diagnostic imaging (especially X-rays) or onward referral to public hospitals. All of these lead to rise in health-care costs and the risk of long-term musculoskeletal-related disability. Physiotherapy (which includes but not limited to education, manual therapy, electrotherapy, shockwave therapy, low level Light Amplified Stimulated Emission of Radiation (LASER) therapy, aquatic therapy, Intervertebral Differential Dynamics (IDD) and exercise) is amenable to most cases of musculoskeletal pain. In addition to this, Psychologically-Informed Physical Therapy (PIPT) is employed in addressing physical as well as psychosocial factors of pain such as depression and anxiety; side-effects of opioids.
Access to physiotherapy care is not equitable among Nigerians with musculoskeletal pain. Improving availability and access to physiotherapy (pain therapy with non-pain relieving drugs) is a crucial public health issue as regards the increasing opioids crisis in Nigeria. It is therefore imperative to advocate for funding of physiotherapy service by health-policy makers and insurers.
Writen by Ezinne Ekediegwu, MPT.